About 1 in 5 American women report having two or more chronic diseases. (Organization for Economic Co-operation and Development)
PCORI has funded 78 patient-centered CER studies that focus on conditions that specifically or more often affect women, in addition to a dozen other projects that are focused on engaging more women in the research process. (As of February 2022)
At least 32 PCORI-funded studies relating to women's health specifically focus on reproductive and perinatal health. (As of February 2022)
PCORI Funding Announcements
On May 3, 2022, PCORI's Online System opened for submissions of Letters of Intent and applications for the following PCORI Funding Announcements, which have elements relating to maternal health and related issues. The Broad Pragmatic Studies PFA includes two special areas of emphasis: Aspirin to Prevent of Preeclampsia and Optimizing Prevention and Treatment of Postpartum Hemorrhage. LOIs were due on June 1.
Study Results that Support Better-Informed Decisions
A Risk-Based Approach for Triaging Mammography Examinations
An algorithm based on clinical indication, breast symptoms, breast cancer history, and age successfully maximized cancer detection, according to this PCORI-funded study‘s research team. Reporting in JAMA Network Open, the study found that 12 percent of mammograms with very high or high cancer detection rates accounted for 55 percent of detected cancers, while 44 percent of mammograms with very low cancer detection rate accounted for just 13 percent of detected cancers.
The findings suggest that triaging individuals most likely to have cancer detected during periods of reduced capacity, such as the COVID-19 pandemic, could result in detecting the most cancers while performing the fewest examinations compared with a non-risk-based approach.
Individualized Patient Decision Making for Treatment Choices among Minorities with Lupus
Lupus is an illness in which the immune system attacks parts of the body; it primarily affects young women. Lupus can cause a kidney disease called lupus nephritis, a swelling of the kidneys. Lupus nephritis is more common and severe in minority groups.
In this PCORI-funded study, based at the University of Alabama at Birmingham, the research team made an online decision aid specifically for women with lupus nephritis to help them make choices about available treatments. They then compared the use of this tool with reading an educational pamphlet about lupus. They found that compared with women who read the pamphlet, women who used the decision aid felt less doubt about their choices
2021 PCORI Virtual Annual Meeting
The 2021 meeting included a breakout session relating to women's health.
Women's Health Study Spotlights
Evidence for Decisions from PCORI-Funded Studies
Evidence Updates: Treating Urinary Incontinence in Women without Surgery
Millions of women experience urinary incontinence; however, many women don’t seek treatment because they don’t realize that improvement is possible.
A recent review of research found that several nonsurgical treatments for urinary incontinence can help.
Evidence Visualization: Effect of Pelvic Floor Muscle Training on Urinary Incontinence
This interactive visualization on pelvic floor muscle training, or PFMT, uses data from randomized controlled trials to assess the efficacy of PFMT to treat urinary incontinence, or UI.
It stemmed from a PCORI-funded systematic review on nonsurgical treatments for urinary incontinence. Pelvic floor exercises were also highlighted as an effective nonsurgical treatment for UI in the Evidence Updates.