Addressing Disparities


The estimated number of Americans who live in rural areas that are more likely than their urban counterparts to die from heart disease, cancer, and stroke. (Source: CDC)


The percentage of the population that belongs to a racial or ethnic minority group, but some minorities experience a disproportionate healthcare burden. (Source: CDC)


The number of clinical effectiveness research studies and related projects that PCORI has funded to help patients at risk for disparities and those who care for them make better-informed decisions about their options to improve their health. (As of February 2022)

Evidence Map and Visualization

Social Needs Interventions to Improve Health Outcomes

Social needs refer to adverse social conditions that are associated with poor health and are identified or prioritized based on patients' perspectives. Addressing these social needs could help improve health outcomes and reduce disparities.

This new interactive visualization and an accompanying report summarize the findings from a systematic scoping review of studies on social needs interventions that reported behavioral outcomes, health outcomes, or health care utilization outcomes.

Read a recent blog post about the evidence visualization.

Study Results that Support Better-Informed Decisions

The PREPARE Study: Reducing the Impact of Asthma on Underserved Populations

An easy-to-use, patient-centered approach to managing moderate to severe asthma improved outcomes for African-American/Black and Hispanic/Latinx adults, according to findings of the PCORI-funded PREPARE study, published in The New England Journal of Medicine. The study was led by Elliot Israel, MD, at Brigham and Women's Hospital in Massachusetts.

Study participants were randomized to receive either usual care or one-time instruction to use inhaled corticosteroids (ICS) when they used an asthma reliever or nebulizer. Those in the ICS group experienced a 15 percent decreased risk of severe asthma exacerbations as well as reduced asthma symptoms and days of impairment compared to those who got usual care.

PCORI Funding Announcements

On May 3, 2022, PCORI's Online System opened for submissions of Letters of Intent (LOI) and applications for the following PCORI Funding Announcements, which have elements relating to addressing disparities in health care and achieving health equity. LOIs were due on June 1.

2021 PCORI Virtual Annual Meeting

The 2021 meeting included a pair of plenary sessions and three breakout sessions relating to addressing disparities and health equity.

Addressing Disparities Study Spotlights

Addressing Disparities Study Spotlight

Research Addressing Health Disparities in Heart Disease

This PCORI-funded project compared usual care to involving community health workers in an effort to reduce cardiovascular disease risks factors in people living in rural Appalachian Kentucky, which has among the worst cardiovascular health profiles in the country.